Volume 9, Issue 2 (5-2021)
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95% of human genes transcribe more than one transcript and generate variant protein isoforms tumors have irregular splicing pattern alternative splicing process are common occurrence and can be used as novel therapeutic biomarkers.
P. 5-16
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There is an association between poor oral health and mental health. Dental anxiety has negative impact on oral health. A higher level of anxiety is associated with fewer filled teeth and higher calculus index. Therefore, in this prospective research, we use DMFT index to evaluate oral health status based on mental and psychological profile of 9967 subjects in Shahedieh, Yazd province.
Simultaneous Effect of Resistance Training and Alpha Lipoic Acid on LC3-1 and P62 Gene Expression of Fatty Liver Diabetic Male Rats
P. 17-26
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Fatty liver may be associated with autophagy. Supplementation with exercise increases the synergistic effects of regulating and improving the disorder. In this experimental study, some indicators of autophagy under the influence of alpha lipoic acid and strength training were investigated. Improvement of inflammatory, oxidative and autophagy factors was a common result of supplementation and exercise.
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Immunotheray is stimulating body’s own immune system to work strongly or smartly to attack on cancer cells. Freund Adjuvant can be effective in immunotherapy for cancer by stimulating immune cells such as dendritic cells and T-cells and increasing the secretion of IFN-γ and other cytokines.
Evaluation of CITED4 Gene Expression in The Cardiac Muscle of Male Rats as a Result of Resistance Exercise and Spirulina Supplement
P. 36-44
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Exercise increases CITED4 levels in the heart and is sufficient to cause physiological hypertrophy. Spirulina supplementation alone has no effect on the signaling pathway of cardiac hypertrophy. If used concomitantly with resistance training, it can affect the signal pathway of cardiac hypertrophy
Investigation of the Effects of Methylphenidate and Endurance Exercise on Structural Changes in Brain Tissue of Male Rats with Hyperactivity
P. 45-54
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Exercise can be an alternative to the use of drugs such as methylphenidate. It is possible to emphasize the need for endurance exercise to reduce blood pressure and treat hyperactivity.
Investigating the Response of Lipid Profile, Insulin Resistance and Mitochondrial Biogenesis of Obese Rats to Various Training
P. 55-67
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Interpretation and diagnosis of the underlying molecular mechanisms of obesity and metabolic syndrome has been one of the most widely performed activities in modern medicine. Exercise training has been suggested as a healthy and promising intervention for obese and overweight people.
Evaluation of Bleaching with Carbamide Peroxide on Microhardness, Mineral Content, and Color Change of White Spot Lesions
P. 68-78
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There is an association between the white lesions on changes in the mineral content of teeth and consequently, changes in tooth hardness, also Tooth bleaching changes the microhardness and mineral content and color of the tooth. Therefore in this study, evaluate the effect of bleaching with 10% carbamide peroxide on the color, microhardness, and mineral content of white spot lesions.
